Nucleosides and Analogues
Medchemexpress LLC Adenosine receptor antagonist 3 | 2400864-80-2 | 97.1% | C16H14N6S | 10MG
Adenosine receptor antagonist 3 is a small-molecule research compound that antagonizes adenosine receptors and is used in in vitro pharmacology and GPCR/G protein signaling studies. Supplied as a light-yellow solid and as a 10 mM solution in DMSO, it has a reported purity of 97.1% and molecular formula C16H14N6S.
Medchemexpress LLC Adenosine receptor inhibitor 1 | 2550400-52-5 | 98.29% | 395.82 | 5 MG
Adenosine receptor inhibitor 1 is a potent and selective adenosine receptor (AR) inhibitor with Ki values of >1000, 68.5, >1000, >1000 nM for A1AR, A2AAR, A2BAR, A3AR, respectively. It exhibits antinociceptive, anti-inflammatory, and peripheral analgesic effects, with potential for research in cancer or neurodegenerative diseases.
- Appearance: solid, white to off-white
- Ki values for A1AR, A2AAR, A2BAR, A3AR
- Metabolic stability in mouse and rat liver microsomes
- Antinociceptive activity
- Anti-inflammatory effect
- Peripheral analgesic effect
Medchemexpress LLC 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl- | 26578-09-6 | 98.0% | 283.24 | 1 ML
L-Guanosine is the L-configuration of Guanosine, a purine nucleoside with anti-herpesvirus activity. It can be used to prepare supramolecular hydrogel and is intended for research use only.
- L-configuration of Guanosine
- Purine nucleoside
- Anti-herpesvirus activity
- Can be used to prepare supramolecular hydrogel
- Intended for research use only
Medchemexpress LLC 6H-purin-6-one, 2-amino-1,9-dihydro-9-β-l-ribofuranosyl- | 26578-09-6 | 98.0% | 283.24 | 50 MG
L-Guanosine is the L-configuration of Guanosine, a purine nucleoside with anti-herpesvirus activity. It can be utilized in the preparation of supramolecular hydrogel.
- L-configuration of guanosine
- Purine nucleoside with anti-herpesvirus activity
- Utilized in the preparation of supramolecular hydrogel
Medchemexpress LLC Adenosine 3',5'-diphosphate disodium | 75431-54-8 | 99.1% | 471.16 | 1 MG
Adenosine 3',5'-diphosphate disodium is an hydroxysteroid sulfotransferases inhibitor. It is for research use only and not sold to patients.
- Hydroxysteroid sulfotransferases inhibitor
- For research use only
- Not sold to patients
- Soluble in H2O at ≥ 25 mg/mL (53.06 mM)
- Store at -20°C, sealed, away from moisture
- In solvent, store at -80°C (6 months) or -20°C (1 month), sealed, away from moisture
Medchemexpress LLC 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl- | 26578-09-6 | 98.0% | 283.24 | 250 MG
L-Guanosine is the L-configuration of Guanosine. This purine nucleoside exhibits anti-herpesvirus activity and can be used in the preparation of supramolecular hydrogel.
- L-configuration of guanosine
- Purine nucleoside
- Exhibits anti-herpesvirus activity
- Can be used in the preparation of supramolecular hydrogel
- Functions as a nucleoside antimetabolite/analog
- Acts as an inhibitor
Medchemexpress LLC L-Guanosine | 26578-09-6 | 98.0% | 283.24 | 25 MG
L-Guanosine is the L-configuration of Guanosine. It is a purine nucleoside that exhibits anti-herpesvirus activity and can be used to prepare supramolecular hydrogel. This product ships at room temperature and should be stored solid at 4°C, protected from light. Solutions can be stored at -80°C for 6 months or -20°C for 1 month, also protected from light.
- Purine nucleoside
- Exhibits anti-herpesvirus activity
- Can be used to prepare supramolecular hydrogel
- Ships at room temperature
- Solid storage: 4°C, protect from light
- In solvent storage: -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC 2H-Pyrazolo[3,4-d]pyrimidin-4-amine, 6-(3-isothiazolyl)-2-[(3-methylphenyl)methyl]- | 2400864-80-2 | 99.1% | C16H14N6S | 1 ML
Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor with potential applications in cancer research. It presents as a light yellow to yellow solid.
- Potent antagonist of adenosine receptor
- Potential for cancer research applications
- Light yellow to yellow solid appearance
- Molecular weight: 322.39
- Purity: 99.12%
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Solvent for solutions: DMSO
Medchemexpress LLC Acyclovir triphosphate sodium | 221119-43-3 | 99.7% | C8H14N5O12P3.xNa | 25 MG
Acyclovir triphosphate sodium (AcycloGTP sodium) is a derivative of Acyclovir that functions as an inhibitor of viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). This compound is also recognized as an inhibitor of HIV-1 reverse transcriptase, ultimately leading to the termination of viral DNA synthesis. It is intended for research use only.
- Competitively inhibits viral DNA polymerase.
- Acts as an analog to deoxyguanosine triphosphate (dGTP).
- Inhibits HIV-1 reverse transcriptase.
- Causes termination of viral DNA synthesis.
- Available for research purposes.
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 100 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist. It exhibits anti-tumor activity by inhibiting tumor growth in vivo. This compound is characterized by its potent inhibitory concentrations for both A2a and A2b adenosine receptors.
- Orally active A2a/A2b adenosine receptor antagonist
- IC50 of 1 nM for A2a adenosine receptor
- IC50 of 3 nM for A2b adenosine receptor
- Exhibits anti-tumor activity
- Inhibits tumor growth in female C57BL/6 mice
- Demonstrates specific pharmacokinetic profiles in mice studies
Medchemexpress LLC ATP-polyamine-biotin | 1800401-93-7 | 98.1% | 25 MG
ATP-polyamine-biotin is the first cell-permeable ATP analogue and serves as an efficient kinase cosubstrate. It promotes biotin labeling of kinase substrates in live cells.
- First cell-permeable ATP analogue
- Efficient kinase cosubstrate
- Promotes biotin labeling of kinase substrates in live cells
Medchemexpress LLC L-adenosine | 3080-29-3 | MFCD01075784 | 99.8% | 267.24 g/mol | C10H13N5O4 | 50 MG
L-adenosine is an enantiomeric analog of adenosine used as a research reagent and a weak adenosine deaminase (ADA) inhibitor (reported Ki = 385 μM). It is supplied as a high-purity solid for studies of adenosine uptake, accumulation, and ADA-related metabolism.
- High purity - 99.82% (reported).
- Suitable for adenosine uptake and accumulation studies.
- Weak ADA inhibitor (Ki ≈ 385 μM).
- Available as a 50 MG solid; additional pack sizes and DMSO solutions are offered.
- Molecular weight 267.24 g/mol; formula C10H13N5O4.
Medchemexpress LLC Guanosine 5'-triphosphate (trisodium salt) | 36051-31-7 | 95.0% | 1 G
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. It promotes myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. This product holds promise for research in biosynthesis and skeletal muscle regeneration.
- G protein signaling activator
- High-energy precursor in biosynthesis of nucleotide units in DNA and RNA
- Promotes myogenic cell differentiation
- Induces release of exosomes from human myogenic precursor cells
- Suitable for research in biosynthesis
- Suitable for research in skeletal muscle regeneration
Medchemexpress LLC Adenosine receptor antagonist 3 | 2400864-80-2 | 99.1% | C16H14N6S | 25 MG
Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. It has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1). This product is for research use only and not for sale to patients. For optimal storage, powder should be kept at -20°C for 3 years or 4°C for 2 years. If in solvent, store at -80°C for 6 months or -20°C for 1 month. Once prepared, aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
- Potent antagonist of adenosine receptor
- Potential for cancer disease research
Medchemexpress LLC 6-O-methyl guanosine | 7803-88-5 | MFCD01723912 | 99.7% | 297.27 g·mol⁻1 | C11H15N5O5 | 5 MG
6-O-methyl guanosine is a modified nucleoside for biochemical research, reported to inhibit colony-forming ability in certain xeroderma pigmentosum cell lines. It is supplied as a solid reagent intended for in vitro studies and analytical applications.
- High purity (99.7%) suitable for analytical and biological experiments.
- Molecular weight 297.27 g·mol⁻1; formula C11H15N5O5.
- Soluble in DMSO (130 mg/mL); sparingly soluble in water (2 mg/mL); ultrasonic or warming recommended to aid dissolution.
- Stable as a powder at -20°C for extended storage.
- Available in small research quantities (for example, 5 mg) for laboratory use.